Corona-Krise: Offener Brief an die Bundeskanzlerin von Prof. Sucharit Bhakdi – OPEN LETTER TO MERKEL – Covid 19 Video

Prof. Dr. med. Sucharit Bhakdi, Facharzt für Mikrobiologie und Infektionsepidemiolgie, leitete 22 Jahre das Institut für Medizinische Mikrobiologie und Hygiene der Universität Mainz. Er hat einen offenen Brief an die Bundeskanzlerin geschrieben mit 5 Fragen, die nach sofortigen Antworten verlangen, um festzustellen, wie begründet die derzeitigen massiven Einschränkungen unserer Grundrechte sind. Das Video erläutert die Fragen und deren Hintergrund.

Aus Platzgründen hier nur das Anschreiben. Der ganze Brief im Wortlaut mit den Fragen und Hintergünden kann unter anderem hier eingesehen werden:
Offener Brief von Professor Sucharit Bhakdi an Bundeskanzlerin Dr. Angela Merkel
ENGLISH:Open Letter from Professor Sucharit Bhakdi to German Chancellor Dr. Angela Merkel
Open Letter from Professor Sucharit Bhakdi to German Chancellor Dr. Angela Merkel

Sehr geehrte Frau Bundeskanzlerin,

Als Emeritus der Johannes-Gutenberg-Universität in Mainz und langjähriger Leiter des dortigen Instituts für Medizinische Mikrobiologie und Hygiene fühle ich mich verpflichtet, die weitreichenden Einschränkungen des öffentlichen Lebens, die wir derzeit auf uns nehmen, um die Ausbreitung des COVID-19 Virus zu reduzieren, kritisch zu hinterfragen.
Es ist ausdrücklich nicht mein Anliegen, die Gefahren der Viruserkrankung herunterzuspielen oder eine politische Botschaft zu kolportieren. Jedoch empfinde ich es als meine Pflicht, einen wissenschaftlichen Beitrag dazu zu leisten, die derzeitige Datenlage richtig einzuordnen, die Fakten, die wir bislang kennen, in Perspektive zu setzen – und darüberhinaus auch Fragen zu stellen, die in der hitzigen Diskussion unterzugehen drohen.
Der Grund meiner Besorgnis liegt vor allem in den wirklich unabsehbaren sozio-ökonomischen Folgen der drastischen Eindämmungsmaßnahmen, die derzeit in weiten Teilen Europas Anwendungen finden und auch in Deutschland bereits in großem Maße praktiziert werden.
Mein Wunsch ist es, kritisch – und mit der gebotenen Weitsicht – über die Vor- und Nachteile einer Einschränkung des öffentlichen Lebens und die daraus resultierenden Langzeiteffekte zu diskutieren.
Dazu stellen sich mir fünf Fragen, die bislang nur unzureichend beantwortet wurden, aber für eine ausgewogene Analyse unentbehrlich sind.
Ich bitte Sie hiermit um rasche Stellungnahme und appelliere gleichsam an die Bundesregierung, Strategien zu erarbeiten, die Risikogruppen effektiv schützen, ohne das öffentliche Leben flächendeckend zu beschneiden und die Saat für eine noch intensivere Polarisierung der Gesellschaft säen, als sie ohnehin schon stattfindet.
Mit vorzüglicher Hochachtung,

Prof. em. Dr. med. Sucharit Bhakdi
——
An Open Letter from Dr. Sucharit Bhakdi, Professor Emeritus of Medical Microbiology at the Johannes Gutenberg University Mainz, to the German Chancellor Dr. Angela Merkel. Professor Bhakdi calls for an urgent re-evaluation of the response to Covid-19 and asks the Chancellor five crucial questions. The let­ter is dated 26 March 2020. This is an inofficial translation; see the original letter in German as a PDF.
Open Letter

Dear Chancellor,

As Emeritus of the Johannes-Gutenberg-University in Mainz and longtime director of the Institute for Medical Microbiology, I feel obliged to critically question the far-reaching restrictions on public life that we are currently taking on ourselves in order to reduce the spread of the COVID-19 virus.

It is expressly not my intention to play down the dangers of the virus or to spread a political message. However, I feel it is my duty to make a scientific contribution to putting the current data and facts into perspective – and, in addition, to ask questions that are in danger of being lost in the heated debate.

The reason for my concern lies above all in the truly unforeseeable socio-economic consequences of the drastic containment measures which are currently being applied in large parts of Europe and which are also already being practiced on a large scale in Germany.

My wish is to discuss critically – and with the necessary foresight – the advantages and disadvantages of restricting public life and the resulting long-term effects.

To this end, I am confronted with five questions which have not been answered sufficiently so far, but which are indispensable for a balanced analysis.

I would like to ask you to comment quickly and, at the same time, appeal to the Federal Government to develop strategies that effectively protect risk groups without restricting public life across the board and sow the seeds for an even more intensive polarization of society than is already taking place.

With the utmost respect,

Prof. em. Dr. med. Sucharit Bhakdi
1. Statistics

In infectiology – founded by Robert Koch himself – a traditional distinction is made between infection and disease. An illness requires a clinical manifestation. [1] Therefore, only patients with symptoms such as fever or cough should be included in the statistics as new cases.

In other words, a new infection – as measured by the COVID-19 test – does not necessarily mean that we are dealing with a newly ill patient who needs a hospital bed. However, it is currently assumed that five percent of all infected people become seriously ill and require ventilation. Projections based on this estimate suggest that the healthcare system could be overburdened.

My question: Did the projections make a distinction between symptom-free infected people and actual, sick patients – i.e. people who develop symptoms?
2. Dangerousness

A number of coronaviruses have been circulating for a long time – largely unnoticed by the media. [2] If it should turn out that the COVID-19 virus should not be ascribed a significantly higher risk potential than the already circulating corona viruses, all countermeasures would obviously become unnecessary.

The internationally recognized International Journal of Antimicrobial Agents will soon publish a paper that addresses exactly this question. Preliminary results of the study can already be seen today and lead to the conclusion that the new virus is NOT different from traditional corona viruses in terms of dangerousness. The authors express this in the title of their paper „SARS-CoV-2: Fear versus Data“. [3]

My question: How does the current workload of intensive care units with patients with diagnosed COVID-19 compare to other coronavirus infections, and to what extent will this data be taken into account in further decision-making by the federal government? In addition: Has the above study been taken into account in the planning so far? Here too, of course, „diagnosed“ means that the virus plays a decisive role in the patient’s state of illness, and not that previous illnesses play a greater role.
3. Dissemination

According to a report in the Süddeutsche Zeitung, not even the much-cited Robert Koch Institute knows exactly how much is tested for COVID-19. It is a fact, however, that a rapid increase in the number of cases has recently been observed in Germany as the volume of tests increases. [4]

It is therefore reasonable to suspect that the virus has already spread unnoticed in the healthy population. This would have two consequences: firstly, it would mean that the official death rate – on 26 March 2020, for example, there were 206 deaths from around 37,300 infections, or 0.55 percent [5] – is too high; and secondly, it would mean that it would hardly be possible to prevent the virus from spreading in the healthy population.

My question: Has there already been a random sample of the healthy general population to validate the real spread of the virus, or is this planned in the near future?
4. Mortality

The fear of a rise in the death rate in Germany (currently 0.55 percent) is currently the subject of particularly intense media attention. Many people are worried that it could shoot up like in Italy (10 percent) and Spain (7 percent) if action is not taken in time.

At the same time, the mistake is being made worldwide to report virus-related deaths as soon as it is established that the virus was present at the time of death – regardless of other factors. This violates a basic principle of infectiology: only when it is certain that an agent has played a significant role in the disease or death may a diagnosis be made. The Association of the Scientific Medical Societies of Germany expressly writes in its guidelines: „In addition to the cause of death, a causal chain must be stated, with the corresponding underlying disease in third place on the death certificate. Occasionally, four-linked causal chains must also be stated.“ [6]

At present there is no official information on whether, at least in retrospect, more critical analyses of medical records have been undertaken to determine how many deaths were actually caused by the virus.

My question: Has Germany simply followed this trend of a COVID-19 general suspicion? And: is it intended to continue this categorisation uncritically as in other countries? How, then, is a distinction to be made between genuine corona-related deaths and accidental virus presence at the time of death?
5. Comparability

The appalling situation in Italy is repeatedly used as a reference scenario. However, the true role of the virus in that country is completely unclear for many reasons – not only because points 3 and 4 above also apply here, but also because exceptional external factors exist which make these regions particularly vulnerable.

One of these factors is the increased air pollution in the north of Italy. According to WHO estimates, this situation, even without the virus, led to over 8,000 additional deaths per year in 2006 in the 13 largest cities in Italy alone. [7] The situation has not changed significantly since then. [8] Finally, it has also been shown that air pollution greatly increases the risk of viral lung diseases in very young and elderly people. [9]

Moreover, 27.4 percent of the particularly vulnerable population in this country live with young people, and in Spain as many as 33.5 percent. In Germany, the figure is only seven percent [10]. In addition, according to Prof. Dr. Reinhard Busse, head of the Department of Management in Health Care at the TU Berlin, Germany is significantly better equipped than Italy in terms of intensive care units – by a factor of about 2.5 [11].

My question: What efforts are being made to make the population aware of these elementary differences and to make people understand that scenarios like those in Italy or Spain are not realistic here?
References:

[1] Fachwörterbuch Infektionsschutz und Infektionsepidemiologie. Fachwörter – Definitionen – Interpretationen. Robert Koch-Institut, Berlin 2015. (abgerufen am 26.3.2020)

[2] Killerby et al., Human Coronavirus Circulation in the United States 2014–2017. J Clin Virol. 2018, 101, 52-56

[3] Roussel et al. SARS-CoV-2: Fear Versus Data. Int. J. Antimicrob. Agents 2020, 105947

[4] Charisius, H. Covid-19: Wie gut testet Deutschland? Süddeutsche Zeitung. (abgerufen am 27.3.2020)

[5] Johns Hopkins University, Coronavirus Resource Center. 2020. (abgerufen am 26.3.2020)

[6] S1-Leitlinie 054-001, Regeln zur Durchführung der ärztlichen Leichenschau. AWMF Online (abgerufen am 26.3.2020)

[7] Martuzzi et al. Health Impact of PM10 and Ozone in 13 Italian Cities. World Health Organization Regional Office for Europe. WHOLIS number E88700 2006

[8] European Environment Agency, Air Pollution Country Fact Sheets 2019, (abgerufen am 26.3.2020)

[9] Croft et al. The Association between Respiratory Infection and Air Pollution in the Setting of Air Quality Policy and Economic Change. Ann. Am. Thorac. Soc. 2019, 16, 321–330.

[10] United Nations, Department of Economic and Social Affairs, Population Division. Living Arrange­ments of Older Persons: A Report on an Expanded International Dataset (ST/ESA/SER.A/407). 2017

[11] Deutsches Ärzteblatt, Überlastung deutscher Krankenhäuser durch COVID-19 laut Experten unwahrscheinlich, (abgerufen am 26.3.2020)

Professor Sucharit Bhakdi explaining his Open Letter (turn on subtitles and translation):

2 Gedanken zu “Corona-Krise: Offener Brief an die Bundeskanzlerin von Prof. Sucharit Bhakdi – OPEN LETTER TO MERKEL – Covid 19 Video

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